Understanding how microtubules function in cells
Dynamic architecture and function of microtubule networks
This study is looking at tiny structures in our cells called microtubules that help move things around, and it's trying to understand how they work and change to support different cell activities, which could help us learn more about diseases that happen when these structures don't function properly.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-11052547 on NIH RePORTER |
What this research studies
This research investigates the dynamic structures known as microtubules, which play a crucial role in transporting materials within cells. By examining how microtubules are organized and regulated, the study aims to uncover the mechanisms that allow them to adapt to various cellular functions. The approach involves analyzing the geometry of microtubules and their interactions with molecular motors and other cellular components. This research could lead to insights into how disruptions in microtubule function contribute to diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions linked to cellular transport issues, such as neurodegenerative diseases or cancer.
Not a fit: Patients with conditions unrelated to cellular transport or microtubule function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cellular processes and lead to new treatments for diseases caused by microtubule dysfunction.
How similar studies have performed: Previous research has shown that understanding microtubule dynamics can lead to significant advancements in cell biology and treatment strategies, indicating a promising avenue for further exploration.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Kaverina, Irina — Vanderbilt University
- Study coordinator: Kaverina, Irina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.