Understanding how microtubules form and organize in cells
Official title: Building Dendrite Architecture via Microtubule Nucleation
Funded at Princeton University · NIH-11032466 · Data updated 2026-11-12
This study is looking at how tiny structures in our cells, called microtubules, are formed and organized during cell division, which is important for keeping our cells healthy and functioning properly.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project start | September 10, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $125,000 |
| NIH project number | 1K99GM157463-01 |
| Project ID | NIH-11032466 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that affect cellular function or diseases related to cell division, such as cancer.
✕Less likely to help
Patients with conditions unrelated to cellular architecture or microtubule function may not benefit from this research.
What this research studies
This research investigates the mechanisms behind the formation and organization of microtubules, which are essential components of the cell's structure. By focusing on how these microtubules nucleate and branch during cell division, particularly in the context of the mitotic spindle, the research aims to uncover the biochemical pathways that regulate these processes. Using advanced laboratory techniques, the study will explore how specific proteins interact to facilitate microtubule assembly, which is crucial for proper cell function and division.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cellular processes that may improve treatments for diseases related to cell division and structure.
How similar studies have gone: Previous research has shown promising results in understanding microtubule dynamics, indicating that this approach has potential for significant discoveries.
Where this research is happening
-
Princeton University
Princeton, United States Active
Researchers
- Principal investigator: Kraus, Jodi — Princeton University
- Study coordinator: Kraus, Jodi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.