Understanding how microtubules form and organize in cells
Building Dendrite Architecture via Microtubule Nucleation
This study is looking at how tiny structures in our cells, called microtubules, are formed and organized during cell division, which is important for keeping our cells healthy and functioning properly.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Princeton University NIH-funded |
| Lab location | 1 site (Princeton, UNITED STATES) |
| Project ID | NIH-11032466 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind the formation and organization of microtubules, which are essential components of the cell's structure. By focusing on how these microtubules nucleate and branch during cell division, particularly in the context of the mitotic spindle, the research aims to uncover the biochemical pathways that regulate these processes. Using advanced laboratory techniques, the study will explore how specific proteins interact to facilitate microtubule assembly, which is crucial for proper cell function and division.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that affect cellular function or diseases related to cell division, such as cancer.
Not a fit: Patients with conditions unrelated to cellular architecture or microtubule function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into cellular processes that may improve treatments for diseases related to cell division and structure.
How similar studies have performed: Previous research has shown promising results in understanding microtubule dynamics, indicating that this approach has potential for significant discoveries.
Where this research is happening
Princeton, UNITED STATES
- Princeton University — Princeton, United States (Active)
Researchers
- Principal investigator: Kraus, Jodi — Princeton University
- Study coordinator: Kraus, Jodi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.