Understanding how microtubules and gene expression machinery work together
Structural studies of function and regulation of microtubules and transcriptional gene expression machinery
This study is looking at tiny structures in our cells called microtubules and how they help control gene activity, with the hope that understanding these processes better could lead to new treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-10993536 on NIH RePORTER |
What this research studies
This research focuses on exploring the structure and function of microtubules and the machinery involved in gene expression. Using advanced techniques like cryo-electron microscopy, the team investigates how these cellular components interact and are regulated. By examining the dynamics of microtubules and their role in cellular processes, the research aims to uncover the molecular mechanisms that govern their function. Patients may benefit from insights gained about cellular processes that could lead to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with conditions linked to microtubule dysfunction or gene expression abnormalities.
Not a fit: Patients with unrelated health issues or those not affected by cellular or genetic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases related to cellular dysfunction and gene regulation.
How similar studies have performed: Other research has shown success in understanding cellular mechanisms through similar structural biology approaches, indicating a promising avenue for this investigation.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Nogales, Eva — University of California Berkeley
- Study coordinator: Nogales, Eva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.