Understanding how microtubules and gene expression machinery work together
Structural studies of function and regulation of microtubules and transcriptional gene expression machinery
This study is looking at tiny structures in our cells called microtubules and how they help control gene expression, with the goal of finding new ways to treat diseases by understanding how these parts work together.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-10904741 on NIH RePORTER |
What this research studies
This research investigates the structural and functional dynamics of microtubules and the machinery involved in gene expression. Using advanced techniques like cryo-electron microscopy and biochemical assays, the team aims to uncover how these cellular components interact and are regulated. By studying the mechanisms that govern microtubule function and their role in cellular processes, the research seeks to provide insights into fundamental biological functions that could impact various diseases. Patients may benefit from a deeper understanding of these processes, which could lead to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions linked to microtubule abnormalities or transcriptional dysregulation.
Not a fit: Patients with unrelated conditions or those not affected by microtubule or gene expression issues may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for diseases related to microtubule dysfunction and gene regulation.
How similar studies have performed: Previous research has shown promising results in understanding microtubule dynamics and gene expression, indicating that this approach has potential for success.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Nogales, Eva — University of California Berkeley
- Study coordinator: Nogales, Eva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.