Understanding how microcalcifications affect atherosclerotic plaque stability
Microcalcifications in Atherosclerotic Plaque
This study is looking at tiny calcium deposits in artery plaques to understand how they might make heart problems more likely, and it aims to find better ways to tell if someone is at risk for heart attacks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | City College of New York NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10884313 on NIH RePORTER |
What this research studies
This research investigates the role of microcalcifications in atherosclerotic plaques, which can lead to serious cardiovascular events like heart attacks. The study aims to explore how various factors, including plaque morphology and biological environment, contribute to the vulnerability of these plaques. By analyzing the mechanical forces and tissue composition, researchers hope to uncover new insights into plaque stability and rupture mechanisms. This could lead to improved methods for assessing cardiovascular risk in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for cardiovascular diseases, particularly those with known atherosclerosis.
Not a fit: Patients without atherosclerotic disease or those who are not at risk for cardiovascular events may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the understanding of plaque stability, potentially leading to better prevention strategies for heart attacks.
How similar studies have performed: Previous research has indicated that understanding the role of calcification in plaque stability could lead to significant advancements in cardiovascular health, suggesting that this approach has potential for success.
Where this research is happening
New York, United States
- City College of New York — New York, United States (Active)
Researchers
- Principal investigator: Cardoso, Luis — City College of New York
- Study coordinator: Cardoso, Luis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.