Understanding how microbial communities respond to invasive species
Official title: DMS/NIGMS 1: Modeling Microbial Community Response to Invasion: A Multi-Omics and Multifacton
Funded at University of Wisconsin-Madison · NIH-10935979 · Data updated 2026-11-12
This study looks at how different groups of bacteria respond when a harmful type called Pseudomonas aeruginosa shows up, and it aims to find ways to help protect these bacteria communities from such invasions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | September 26, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $170,649 |
| NIH project number | 5R01GM152744-02 |
| Project ID | NIH-10935979 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions influenced by microbial community dynamics, such as infections or diseases related to dysbiosis.
✕Less likely to help
Patients with stable microbial communities or those not affected by microbial invasions may not benefit from this research.
What this research studies
This research investigates how complex microbial communities react when faced with invasive species, specifically focusing on the bacterium Pseudomonas aeruginosa. By using a specially designed model community, researchers will analyze the interactions and dynamics within these communities to better understand the underlying principles of their behavior. The study employs advanced techniques, including multi-omics analysis, to gather comprehensive data on molecular interactions and community responses. This approach aims to develop tailored interventions that can help manage or mitigate the effects of invasions on microbial communities.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing microbial communities, which may have implications for human health and environmental stability.
How similar studies have gone: Previous research has shown success in using model microbial communities to understand complex interactions, indicating that this approach has potential for valuable insights.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Sankaran, Kris — University of Wisconsin-Madison
- Study coordinator: Sankaran, Kris
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.