Understanding how methylphenidate affects the brain in PTSD patients
Computational Analysis of Neural Effects of Methylphenidate in Posttraumatic Stress Disorder
This study is looking at how the ADHD medication methylphenidate affects veterans with PTSD, using brain scans and behavior tests to help find better treatment options for those struggling with PTSD symptoms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project ID | NIH-11115539 on NIH RePORTER |
What this research studies
This research investigates the effects of methylphenidate, a medication commonly used to treat ADHD, on individuals with posttraumatic stress disorder (PTSD). By combining computational analysis, pharmacological treatment, and brain imaging techniques, the study aims to uncover how this medication influences complex behaviors associated with PTSD. The goal is to better understand the underlying neural mechanisms of PTSD symptoms and improve treatment options for affected veterans. Participants may undergo assessments that include behavioral evaluations and brain scans to gather comprehensive data.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with posttraumatic stress disorder who may benefit from pharmacological interventions.
Not a fit: Patients who do not have PTSD or those who are not veterans may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, targeted treatments for veterans suffering from PTSD.
How similar studies have performed: Previous studies have shown promising results with similar pharmacological approaches in treating PTSD, indicating potential for success in this research.
Where this research is happening
San Diego, United States
- VA San Diego Healthcare System — San Diego, United States (Active)
Researchers
- Principal investigator: Howlett, Jonathon R — VA San Diego Healthcare System
- Study coordinator: Howlett, Jonathon R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.