Understanding how metals like copper and iron affect cell function and health.
Metalloendocrinology: Mapping Bioinorganic Chemistry in the Extracellular Space
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10845788
This study is looking at how important metals like copper and iron behave in our bodies and how they might affect our health, especially in conditions like cancer and brain diseases, to help us find better ways to spot any imbalances that could lead to these issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10845788 on ClinicalTrials.gov |
What this research studies
This research investigates the role of essential metals, particularly copper and iron, in biological processes and their impact on health. It aims to map the presence and behavior of these metals in the extracellular space, such as blood plasma, to better understand their functions and potential disruptions that can lead to diseases like cancer and neurodegeneration. By developing advanced methods to assess metal speciation, the research seeks to identify subtle imbalances that current techniques may overlook, ultimately improving our understanding of metal-related health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to oxidative stress, such as cancer, neurodegenerative diseases, or metabolic disorders.
Not a fit: Patients without any known issues related to metal imbalances or oxidative stress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for conditions related to metal imbalances, such as cancer and cardiovascular diseases.
How similar studies have performed: While there has been significant research on metal ions in intracellular spaces, this approach to studying extracellular metal speciation is relatively novel and has not been extensively tested.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HEFFERN, MARIE C. — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: HEFFERN, MARIE C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers