Understanding how metabolites move within cells
Official title: Dissecting intracellular metabolite trafficking using chemoproteomics
Funded at University of Wisconsin-Madison · NIH-11089400 · Data updated 2026-11-12
This study is looking at how important substances in our cells move around and interact with proteins, which could help us understand diseases like cancer and metabolic disorders better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $388,750 |
| NIH project number | 5R35GM150899-03 |
| Project ID | NIH-11089400 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions related to metabolic disorders, cancer, or other diseases influenced by cellular signaling.
✕Less likely to help
Patients with conditions unrelated to cellular metabolism or signaling may not benefit from this research.
What this research studies
This research investigates the movement of signaling metabolites within cells, which are crucial for various cellular processes such as cell division and response to environmental changes. By using advanced techniques like chemoproteomics and metabolomics, the study aims to develop new tools to track how these metabolites interact with proteins and their transport within different parts of the cell. This could help uncover the mechanisms behind diseases like cancer and metabolic disorders, providing insights into how cellular functions are regulated.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases linked to metabolite transport dysfunction.
How similar studies have gone: Previous research has shown promising results in understanding cellular signaling mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Galmozzi, Andrea — University of Wisconsin-Madison
- Study coordinator: Galmozzi, Andrea
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.