Understanding how metabolites influence cell behavior
Mechanisms of metabolite signaling
['FUNDING_OTHER'] · UNIVERSITY OF UTAH · NIH-11051197
This study is looking at how tiny substances made by our bodies, called metabolites, interact with proteins to help keep our cells healthy and functioning well, and it's designed for anyone interested in understanding how these processes affect our overall health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF UTAH (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-11051197 on ClinicalTrials.gov |
What this research studies
This research investigates how metabolites, which are the byproducts of metabolism, interact with proteins and other macromolecules to influence cellular functions. Using a novel platform called MIDAS, the team aims to discover and characterize these interactions with high sensitivity. The research will focus on the roles of metabolites in the ubiquitin-proteasome system and autophagy, which are critical for cellular health and function. By exploring these mechanisms, the research seeks to uncover how metabolic signals can affect cell behavior and communication.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with metabolic disorders or conditions that may be influenced by cellular signaling pathways.
Not a fit: Patients with stable metabolic health and no underlying cellular signaling disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into how metabolic processes affect diseases and potentially identify new therapeutic targets.
How similar studies have performed: Other research has shown promising results in understanding metabolite-protein interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- UNIVERSITY OF UTAH — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RUTTER, JARED P — UNIVERSITY OF UTAH
- Study coordinator: RUTTER, JARED P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.