Understanding how metabolites can help diagnose and track sarcoidosis
Official title: Integrative Metabolomics of Sarcoidosis Diagnosis and Progression
Funded at National Jewish Health · NIH-11049526 · Data updated 2026-11-12
This study is looking at how analyzing certain chemicals in the blood can help doctors better diagnose and track sarcoidosis, especially in African American women who may face more challenges with the disease, so that patients can get the care they need more quickly and accurately.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | National Jewish Health NIH-funded |
| Lab location | 1 site (Denver, United States) |
| Project start | April 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $760,374 |
| NIH project number | 1R01HL173239-01A1 |
| Project ID | NIH-11049526 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with sarcoidosis, particularly African American women, who may benefit from improved diagnostic methods.
✕Less likely to help
Patients with sarcoidosis who are not part of the targeted demographic or those with other underlying conditions may not receive direct benefits from this research.
What this research studies
This research investigates the use of metabolomics, which studies the unique chemical fingerprints that specific cellular processes leave behind, to improve the diagnosis and monitoring of sarcoidosis. By analyzing blood samples from patients, the research aims to identify reliable biomarkers that can indicate the presence of the disease and its progression. The study particularly focuses on the differences in metabolomic profiles among diverse populations, including African American women, who are known to have worse outcomes. This approach could lead to more accurate and timely diagnoses, ultimately improving patient care.
Why it matters
Potential benefit: If successful, this research could provide new diagnostic tools and prognostic indicators for sarcoidosis, leading to better management of the disease.
How similar studies have gone: Previous research has shown promise in using metabolomics for disease diagnosis, suggesting that this approach could yield valuable insights for sarcoidosis as well.
Where this research is happening
-
National Jewish Health
Denver, United States Active
Researchers
- Principal investigator: Liao, Shu-Yi — National Jewish Health
- Study coordinator: Liao, Shu-Yi
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.