Understanding how metabolism affects prostate cancer in African American men
Metabolic Rewiring Promotes AA PCa by Regulating Stromal-Epithelial Interaction
This study is looking at how prostate cancer affects African American men differently than European American men by examining tiny molecules in their bodies, with the hope of finding ways to better predict cancer recurrence for African American patients and improve their care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10652987 on NIH RePORTER |
What this research studies
This research investigates the biochemical differences in prostate cancer between African American and European American men using metabolomic profiling. By analyzing metabolites, which are small molecules produced during cellular metabolism, the study aims to uncover unique metabolic pathways that may contribute to the more aggressive nature of prostate cancer in African American men. The goal is to develop a biomarker panel that can predict cancer recurrence specifically for African American patients, addressing health disparities in prostate cancer outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American men diagnosed with prostate cancer.
Not a fit: Patients who are not of African American descent or those without a prostate cancer diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction of prostate cancer recurrence and tailored treatment strategies for African American men.
How similar studies have performed: Previous research has shown promising results in using metabolomic profiling to understand cancer disparities, indicating potential for success in this novel approach.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Sreekumar, Arun — Baylor College of Medicine
- Study coordinator: Sreekumar, Arun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.