Understanding how metabolic changes affect diabetes progression in Mexican Americans
Diabetes Progression with Metabolomic Profiling in Starr County Mexican Americans
This study is looking at how the body’s metabolism changes early on in people who might develop type 2 diabetes, especially focusing on Mexican Americans in Starr County, Texas, to help spot warning signs and understand the role of genetics in diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10553239 on NIH RePORTER |
What this research studies
This research investigates the early metabolic changes associated with the progression of type 2 diabetes, particularly among Mexican Americans in Starr County, Texas. By analyzing metabolomic profiles of 600 individuals over time, the study aims to identify the earliest indicators of diabetes development and the biological processes involved. Participants will be monitored at six different time points, allowing researchers to gather comprehensive data on metabolic changes and their relationship to diabetes risk. The study also incorporates genomic data to enhance understanding of the genetic factors contributing to diabetes progression.
Who could benefit from this research
Good fit: Ideal candidates for this research are Mexican Americans with prediabetes or normal glycemia who are at risk for developing type 2 diabetes.
Not a fit: Patients who already have advanced type 2 diabetes or those outside the Mexican American demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early detection and prevention strategies for type 2 diabetes, ultimately reducing its prevalence and impact.
How similar studies have performed: Previous research has shown promise in using metabolomic profiling to understand diabetes progression, indicating that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Jun, Goo — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Jun, Goo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.