Understanding how mental stress affects heart function in women with coronary microvascular dysfunction
Official title: Mental Stress Reactivity in Women with Coronary Microvascular Dysfunction
Funded at Emory University · NIH-11254974 · Data updated 2026-11-12
This study is looking at how stress affects the heart in women with coronary microvascular dysfunction, hoping to learn more about how stress impacts heart health and find better ways to help manage their symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | January 1, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $135,812 |
| NIH project number | 3R01HL157311-04S1 |
| Project ID | NIH-11254974 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who experience symptoms of heart issues but have been diagnosed with coronary microvascular dysfunction.
✕Less likely to help
Patients who do not have coronary microvascular dysfunction or those with obstructive coronary artery disease may not benefit from this research.
What this research studies
This research investigates how mental stress impacts heart function in women diagnosed with coronary microvascular dysfunction (CMD). It aims to understand the relationship between psychological stress and heart health by measuring how the heart's blood vessels respond to stress. Using advanced imaging techniques, the study will assess the flow of blood in the heart during stress and explore the underlying mechanisms that may contribute to symptoms experienced by these women. The goal is to provide insights that could lead to better treatment options for CMD.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for women suffering from heart-related symptoms despite having no obstructive coronary artery disease.
How similar studies have gone: Previous research has indicated that understanding the effects of stress on heart function can lead to significant advancements in treatment, suggesting that this approach has potential for success.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Mehta, Puja Kiran — Emory University
- Study coordinator: Mehta, Puja Kiran
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.