Understanding how menopause and metabolic health affect cognitive impairment and dementia.
Metabolic and Hormonal Mechanisms of VCID
['FUNDING_R01'] · ALBANY MEDICAL COLLEGE · NIH-11069487
This study is looking at how menopause affects weight and memory in women and is testing a special estrogen treatment to see if it can help improve thinking skills for those experiencing cognitive issues after menopause.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALBANY MEDICAL COLLEGE (nih funded) |
| Locations | 1 site (ALBANY, UNITED STATES) |
| Trial ID | NIH-11069487 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between menopause, metabolic health, and vascular contributions to cognitive impairment and dementia (VCID). It aims to identify new therapeutic approaches specifically for post-menopausal women suffering from VCID. The study explores how menopause leads to weight gain and cognitive decline, and tests the effects of a specific estrogen therapy on cognitive function. By examining the underlying cellular mechanisms, the research seeks to improve understanding and treatment of dementia.
Who could benefit from this research
Good fit: Ideal candidates for this research are post-menopausal women experiencing cognitive impairment or dementia.
Not a fit: Patients who are not post-menopausal or do not have cognitive impairment or dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective therapies that improve cognitive function in post-menopausal women with dementia.
How similar studies have performed: While there is ongoing research into menopause and cognitive health, this specific approach focusing on estrogen signaling in dementia models is relatively novel.
Where this research is happening
ALBANY, UNITED STATES
- ALBANY MEDICAL COLLEGE — ALBANY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZULOAGA, KRISTEN LEANNE — ALBANY MEDICAL COLLEGE
- Study coordinator: ZULOAGA, KRISTEN LEANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia