Understanding how men and women recover from muscle disuse.
Sex-specific determinants of early-phase recovery from skeletal muscle disuse.
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · NIH-10892487
This study is looking at how muscles recover after not being used for a week, and it’s specifically checking for differences between men and women, so if you're a middle-aged adult, you might help us understand how your muscles bounce back during rehab.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-10892487 on ClinicalTrials.gov |
What this research studies
This research investigates the early changes in muscle recovery after a period of disuse, focusing on differences between men and women. Participants will undergo a 7-day period of unilateral leg disuse followed by 14 days of rehabilitation. The study aims to identify molecular changes in muscle tissue and how these changes affect recovery in middle-aged individuals. By analyzing muscle biopsies, researchers hope to uncover sex-specific responses to rehabilitation efforts.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged men and women who may be at risk of muscle disuse and atrophy.
Not a fit: Patients who are younger or do not have a history of muscle disuse may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved rehabilitation strategies tailored to the specific needs of men and women recovering from muscle disuse.
How similar studies have performed: While there is existing research on muscle disuse, this study's focus on sex-specific responses in a middle-aged demographic is relatively novel.
Where this research is happening
SAN ANTONIO, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCIENCE CENTER — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RASMUSSEN, BLAKE B — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- Study coordinator: RASMUSSEN, BLAKE B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.