Understanding how memory works during sleep and wakefulness
Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles
['FUNDING_U01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10910080
This study is looking at how sleep and being awake affect the way our brains form and strengthen memories, especially for people with memory issues like Alzheimer's, to find ways to help improve their memory.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10910080 on ClinicalTrials.gov |
What this research studies
This research investigates the neural mechanisms involved in memory formation and consolidation, particularly focusing on how these processes are affected by sleep and wake cycles. By utilizing advanced methodologies that capture the continuous and multimodal nature of human experiences, the study aims to uncover the brain's activation patterns during memory processing. The goal is to bridge the gap between animal studies and human cognitive research, ultimately leading to potential interventions that could enhance memory function in individuals with neurodegenerative diseases like Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those experiencing significant memory impairment.
Not a fit: Patients with memory disorders unrelated to Alzheimer's or those without cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving memory function in patients suffering from Alzheimer's disease and other memory disorders.
How similar studies have performed: Previous research has shown promise in understanding memory mechanisms, but this approach aims to provide novel insights by integrating human cognitive experiences with advanced neural analysis.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FRIED, ITZHAK — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: FRIED, ITZHAK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease