NIH-funded research R01 grant

Understanding how memory biases affect social anxiety in adolescents

Official title: Neural mechanisms of memory bias in adolescent social anxiety persistence and remittance

Funded at Temple Univ of the Commonwealth · NIH-10994639 · Data updated 2026-11-12

This study is looking at what helps or hinders social anxiety in teenagers, especially how their memories of negative social experiences might play a role, so we can find better ways to help them feel more comfortable in social situations.

More Anxiety research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTemple Univ of the Commonwealth
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startDecember 5, 2023
Project endNovember 30, 2028
Funding year2025
Award (this year)$637,829
NIH project number5R01MH132727-02
Project IDNIH-10994639 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents aged 12 to 20 who experience symptoms of social anxiety.

Less likely to help

Patients who do not have social anxiety or are outside the age range of 12 to 20 may not benefit from this research.

What this research studies

This research investigates the factors that influence whether social anxiety in adolescents persists or remits during critical developmental stages. By focusing on memory biases related to negative social experiences, the study aims to uncover new treatment targets that could help alleviate symptoms. Utilizing advanced techniques such as fMRI and neuromelanin-sensitive MRI, researchers will explore the relationship between dopamine function and brain connectivity in adolescents with social anxiety. The goal is to develop a comprehensive understanding of how these neural mechanisms contribute to anxiety and to identify potential interventions.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for adolescents suffering from social anxiety, improving their quality of life.

How similar studies have gone: Previous research has shown promise in understanding the role of memory biases in anxiety disorders, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Temple Univ of the Commonwealth
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Jarcho, Johanna Molly — Temple Univ of the Commonwealth
  • Study coordinator: Jarcho, Johanna Molly

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.