Understanding how melanoma cells spread early in the disease process
Project 1: Tumor Cell Intrinsic Determinants of Early Dissemination in Melanoma
This study is looking at how melanoma cells change and behave in ways that help them spread early on, with the goal of finding better ways to treat the disease for people affected by it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10900744 on NIH RePORTER |
What this research studies
This research investigates the characteristics of melanoma cells that contribute to their ability to spread early in the disease. By examining the changes in gene expression and cell behavior, the study aims to identify how these cells transition between different states that may influence their aggressiveness and response to treatment. The approach involves analyzing tumor samples to understand the molecular drivers of metastasis and the evolution of diverse cell states within the tumors. This could provide insights into how melanoma progresses and how it might be treated more effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cutaneous melanoma, particularly those in the early stages of the disease.
Not a fit: Patients with advanced melanoma or those who have already undergone extensive treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing melanoma from spreading and enhancing treatment outcomes for patients.
How similar studies have performed: Previous research has shown that understanding the molecular mechanisms of cancer metastasis can lead to significant advancements in treatment strategies, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Hernando, Eva — New York University School of Medicine
- Study coordinator: Hernando, Eva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.