Understanding how medications interact with diseases in older adults

Strengthening the Evidence-Base for Drug-Disease Interactions in Older Adults

['FUNDING_R01'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-10617649

This study is looking at how other health issues in older adults can affect how their medications work, so we can help doctors make safer and more effective treatment choices for their patients.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorRUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded)
Locations1 site (Newark, UNITED STATES)
Trial IDNIH-10617649 on ClinicalTrials.gov

What this research studies

This research investigates how existing diseases in older adults can change the effects of medications they take, particularly focusing on drug-disease interactions (DDSIs). It aims to gather evidence from large patient databases to identify which drug warnings are clinically relevant and which are not. By analyzing data from millions of patients, the research seeks to improve the safety and effectiveness of medication prescriptions for older adults. The goal is to provide healthcare providers with better guidance on personalized treatment options based on solid evidence.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who are taking multiple medications and have one or more chronic diseases.

Not a fit: Patients who are younger or do not have chronic diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective medication management for older adults, reducing the risk of adverse drug effects.

How similar studies have performed: Previous research has shown that understanding drug-disease interactions can significantly improve patient outcomes, indicating that this approach has potential for success.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.