Understanding how mechanical factors influence cancer spread and growth in different organs
Admin: Mechanical determinants of organ-selective metastatic colonization, dormancy and outgrowth
This study looks at how the physical characteristics of cancer cells and their surroundings influence how they spread to other parts of the body and go into a resting state before growing again, with the goal of finding better ways to prevent or treat metastatic cancer for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10911868 on NIH RePORTER |
What this research studies
This research investigates the mechanical factors that affect how cancer cells spread to different organs, enter a dormant state, and later grow. A collaborative team of experts from prestigious institutions will analyze data and develop models to better understand these processes. By focusing on the physical properties of cancer cells and their environment, the research aims to uncover new insights into metastatic behavior. Patients may benefit from improved strategies for preventing or treating metastatic cancer based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with metastatic cancer, particularly those with breast cancer.
Not a fit: Patients with localized cancer that has not spread to other organs may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent cancer from spreading and improve patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding cancer metastasis through mechanical factors, indicating that this approach could yield valuable insights.
Where this research is happening
Cambridge, United States
- Massachusetts Institute of Technology — Cambridge, United States (Active)
Researchers
- Principal investigator: Kamm, Roger D — Massachusetts Institute of Technology
- Study coordinator: Kamm, Roger D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.