Understanding how mechanical factors affect chronic low back pain
Mechanical Biomarkers of Chronic Low Back Pain
This study is looking at how different factors, like the way your spine works and your overall health, affect chronic low back pain, and it's for people who want to understand their pain better and find more effective treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10665590 on NIH RePORTER |
What this research studies
This research investigates the role of mechanical, inflammatory, and biopsychosocial factors in chronic low back pain (LBP) by focusing on the intervertebral disc (IVD). Using advanced imaging techniques, the study aims to quantify the mechanical function of the IVD and explore how it relates to pain perception and other contributing factors. By identifying different phenotypes of LBP, the research seeks to improve the understanding of this complex condition and potentially enhance treatment strategies. Participants may undergo imaging and assessments to help define these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who experience chronic low back pain.
Not a fit: Patients with acute back pain or those without any history of back pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for chronic low back pain.
How similar studies have performed: Previous research has shown promise in using imaging techniques to understand pain mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Goode, Adam — Duke University
- Study coordinator: Goode, Adam
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.