Understanding how MBNL1 helps heart cells develop and function.
Investigating the Role of MBNL1 in Maintaining Cardiomyocyte Terminal Differentiation.
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF WASHINGTON · NIH-10912609
This study is looking at a protein called MBNL1 to understand how heart muscle cells grow and heal after injury, which could help find new treatments for heart diseases that might benefit patients like you.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WASHINGTON (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10912609 on ClinicalTrials.gov |
What this research studies
This research investigates the role of a specific protein, MBNL1, in the development and maintenance of heart muscle cells, known as cardiomyocytes. It focuses on how these cells change after birth and how this affects their ability to grow and regenerate after injury. By studying the mechanisms behind cardiomyocyte differentiation, the research aims to uncover potential pathways that could allow the heart to heal itself more effectively. Patients may benefit from insights that could lead to new treatments for heart diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing cardiac diseases or conditions affecting heart muscle cells.
Not a fit: Patients with non-cardiac conditions or those under 21 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for promoting heart regeneration in patients with cardiac diseases.
How similar studies have performed: While the specific role of MBNL1 in cardiomyocyte differentiation is still being explored, similar studies have shown promise in understanding cardiac regeneration mechanisms.
Where this research is happening
SEATTLE, UNITED STATES
- UNIVERSITY OF WASHINGTON — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAILEY, LOGAN ROBERT JEFFERSON — UNIVERSITY OF WASHINGTON
- Study coordinator: BAILEY, LOGAN ROBERT JEFFERSON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiac Diseases