Understanding how maternal exercise helps offspring health

Longitudinal Imaging of Maternal Exercise and Exerkine Effects on Offspring Metabolism

NIH-funded research University of Maryland Baltimore · NIH-11094108

This project explores how exercise during pregnancy can lead to better health for children by looking at special hormones and body changes.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11094108 on NIH RePORTER

What this research studies

We know that exercise during pregnancy can have lasting positive effects on a child's well-being. This project aims to understand *how* these benefits happen, focusing on special exercise-induced hormones called exerkines. We are developing new imaging tools to track changes in metabolism, specifically in fat tissue, to see how exercise and these hormones affect the body. This work uses advanced imaging techniques to non-invasively detect these metabolic changes in a controlled setting.

Who could benefit from this research

Good fit: This foundational work is for future mothers interested in the long-term health benefits of exercise during pregnancy for their children.

Not a fit: Patients not interested in the mechanisms of maternal exercise or those seeking immediate clinical interventions would not directly benefit from this basic science project.

Why it matters

Potential benefit: If successful, this work could help us better understand the specific ways maternal exercise improves offspring health, potentially leading to new ways to support healthy pregnancies and children.

How similar studies have performed: While the general benefits of maternal exercise are recognized, this project pioneers new imaging methods to precisely track the metabolic effects of exercise and exerkines, making the methodology novel.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.