Understanding how mammographic density relates to breast cancer risk
Genomic and Transcriptomic Analysis of Mammographic Density
This study is looking at how our genes might influence mammographic density, which can affect breast cancer risk, and it's for women who want to understand more about their health and how genetics play a role in breast cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10819733 on NIH RePORTER |
What this research studies
This research investigates the genetic factors associated with mammographic density (MD), which is a significant risk factor for breast cancer. By analyzing gene expression and network information alongside existing genetic data, the study aims to identify specific genes linked to MD. The research involves a large cohort of women and utilizes advanced statistical methods to enhance the accuracy of findings. Ultimately, the goal is to uncover biological mechanisms that connect MD to breast cancer risk, potentially leading to improved risk assessment and prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are women with varying levels of mammographic density who are undergoing routine mammography.
Not a fit: Patients who do not undergo mammographic examinations or those with a history of breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and assessment of breast cancer risk based on mammographic density.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to breast cancer risk, suggesting that this approach may yield valuable insights.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Sieh, Weiva — University of Tx Md Anderson Can Ctr
- Study coordinator: Sieh, Weiva
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.