Understanding how mammals adapt to fruit-eating diets

EDGE CMT: Genomic characterization of mammalian adaptation to frugivory

NIH-funded research University of California, San Francisco · NIH-11004097

This study is looking at how certain mammals, like primates and bats, have developed special genes that help them eat fruit, and it’s for anyone curious about how our diets can affect health and evolution.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11004097 on NIH RePORTER

What this research studies

This research investigates the genetic and molecular factors that enable mammals, particularly primates and bats, to adapt to fruit-based diets. By using advanced genomic techniques, the study aims to identify specific genetic sequences that have evolved in fruit-eating species. The researchers will analyze various tissues from these mammals and validate their findings through laboratory experiments, including gene assays and genetic modifications in mice. This work could provide insights into dietary adaptations and their implications for health.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with a keen interest in genetic factors related to diet and metabolism, particularly those with metabolic disorders.

Not a fit: Patients who do not have an interest in genetic research or those not affected by metabolic diseases may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of dietary adaptations that may inform strategies for managing metabolic diseases in humans.

How similar studies have performed: Other research has shown success in using genomic approaches to understand dietary adaptations in various species, suggesting that this study builds on established methodologies.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.