Understanding how magnetic stimulation affects brain cells in the cerebellum
Cellular Mechanisms of Transcranial Magnetic Stimulation in Cerebellar Cortex
This study is exploring how a treatment called transcranial magnetic stimulation (TMS) affects brain cells in the cerebellum, which helps control movement, to find better ways to use TMS for people who need help with motor control.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10609960 on NIH RePORTER |
What this research studies
This research investigates the cellular mechanisms by which transcranial magnetic stimulation (TMS) activates neurons in the cerebellum, a part of the brain that plays a crucial role in motor control. The study employs a combination of in vitro experiments using turtle cerebellum tissue, computational modeling to simulate electric fields, and human studies to observe eye movement responses. By examining how TMS interacts with brain cells at a cellular level, the research aims to uncover fundamental neural dynamics that could apply to humans. This comprehensive approach may lead to improved applications of TMS in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological or psychiatric disorders who may benefit from TMS therapy.
Not a fit: Patients with conditions unrelated to cerebellar function or those who do not respond to TMS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance the effectiveness of TMS as a treatment for various neurological and psychiatric conditions.
How similar studies have performed: Previous research has shown promising results in using TMS for various brain conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Patel, Padmavathi Sundaram — Massachusetts General Hospital
- Study coordinator: Patel, Padmavathi Sundaram
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.