Understanding how m6A RNA modification affects cancer
Characterization and modeling of m6A RNA methylation in cancer
['FUNDING_R01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10857305
This study is looking at how a specific change in RNA, called m6A, might affect the growth of different types of cancer, like bladder, breast, and skin cancers, to help find new ways to treat these diseases.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-10857305 on ClinicalTrials.gov |
What this research studies
This research investigates the role of N6-methyladenosine (m6A) RNA modification in various cancers, including bladder, breast, and skin cancers. By analyzing large patient cohorts from The Cancer Genome Atlas (TCGA), the study aims to map the patterns of m6A modification and its regulators, which may influence cancer development and progression. The research employs advanced sequencing techniques and protein expression profiling to uncover potential biomarkers and therapeutic targets for cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with bladder, breast, or skin cancers.
Not a fit: Patients with non-malignant conditions or those not diagnosed with the specified cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new biomarkers and targeted therapies for cancer patients.
How similar studies have performed: Previous research has shown promising results in understanding RNA modifications in cancer, indicating that this approach may yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TX MD ANDERSON CAN CTR — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIANG, HAN — UNIVERSITY OF TX MD ANDERSON CAN CTR
- Study coordinator: LIANG, HAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bladder Cancer, Urinary Bladder Cancer, Breast Cancer, Cancers