Understanding how lysosomes transport proteins and their role in cancer and neurodegenerative diseases
Official title: Mapping and Therapeutic Hijacking of Lysosomal Transport
Funded at Stanford University · NIH-10686547 · Data updated 2026-11-12
This study is looking at how tiny parts of our cells, called lysosomes, help manage waste and communicate with other cell parts, which could lead to better treatments for diseases like cancer and brain disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $1,385,226 |
| NIH project number | 1DP2GM154016-01 |
| Project ID | NIH-10686547 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with cancer or neurodegenerative disorders who may benefit from targeted therapies.
✕Less likely to help
Patients with conditions unrelated to lysosomal function or those not diagnosed with cancer or neurodegenerative diseases may not receive benefit from this research.
What this research studies
This research investigates the mechanisms by which lysosomes, the cell's waste disposal and recycling centers, transport proteins and communicate with other parts of the cell. By mapping the interactions between the cell surface and lysosomes, the study aims to uncover how these processes are regulated and how their dysregulation can lead to diseases like cancer and neurodegenerative disorders. The approach involves analyzing various cellular processes such as autophagy and endocytosis to identify potential therapeutic targets for drug delivery. Patients may benefit from insights gained that could lead to new treatments or improved drug delivery systems for their conditions.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that enhance drug delivery and treatment efficacy for cancer and neurodegenerative diseases.
How similar studies have gone: Previous research has shown promising results in targeting lysosomal pathways for drug delivery, indicating that this approach has potential for success.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Banik, Steven — Stanford University
- Study coordinator: Banik, Steven
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.