Understanding how lysosomes affect aging and Alzheimer's disease
Lysosome Regulation and Signaling in Aging and Alzheimer's Disease
This study looks at how tiny parts of our cells called lysosomes, which help break down waste, change as we get older and how this might relate to Alzheimer's disease, with the hope of finding new ways to help manage or prevent the condition.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11051214 on NIH RePORTER |
What this research studies
This research investigates the role of lysosomes, which are cellular structures responsible for breaking down waste, in the processes of aging and Alzheimer's disease. By examining how lysosome regulation and signaling change with age, the study aims to uncover potential mechanisms that contribute to cognitive decline and Alzheimer's symptoms. Patients may benefit from insights gained through this research, which could lead to new therapeutic strategies for managing or preventing Alzheimer's disease. The research employs a combination of cellular and molecular biology techniques to explore these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults aged 21 and older who are experiencing symptoms of Alzheimer's disease or age-related cognitive decline.
Not a fit: Patients under 21 years old or those without any signs of cognitive decline or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that slow down or prevent the progression of Alzheimer's disease and age-related cognitive decline.
How similar studies have performed: Previous research has shown promising results in understanding lysosomal function in aging and neurodegenerative diseases, indicating that this approach has potential for success.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Zheng, Hui — Baylor College of Medicine
- Study coordinator: Zheng, Hui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.