Understanding how lymphatic vessels support brain healing and growth of new neurons
Official title: Lymphatic Support of Neurogenesis and regeneration
Funded at Weill Medical Coll of Cornell Univ · NIH-11002287 · Data updated 2026-11-12
This study is looking at how the lymphatic system in the brain helps create new brain cells and supports healing after injuries like strokes or traumatic brain injuries, using both mammal and zebrafish models to understand how it all works.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $398,657 |
| NIH project number | 5R01NS126209-03 |
| Project ID | NIH-11002287 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced traumatic brain injuries or strokes, particularly adults.
✕Less likely to help
Patients with chronic neurological conditions unrelated to acute brain injuries may not benefit from this research.
What this research studies
This research investigates the role of the lymphatic system in the brain, particularly how it contributes to the generation of new neurons and the healing process after brain injuries such as traumatic brain injury (TBI) and stroke. By studying both mammalian and zebrafish models, the research aims to uncover the mechanisms through which lymphatic vessels influence neurogenesis and recovery. The approach includes examining the signaling pathways involved in lymphatic function and their impact on brain health during injury and recovery phases.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance brain recovery and regeneration after injuries.
How similar studies have gone: Previous studies have shown promising results in understanding lymphatic contributions to regeneration in other organs, suggesting potential for success in this novel area of brain research.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Harrison, Michael — Weill Medical Coll of Cornell Univ
- Study coordinator: Harrison, Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.