Understanding how lymphatic vessels help heal wounds
Official title: Decoding the repair and immunomodulatory functions of lymphatic vessels in wound healing
Funded at Icahn School of Medicine at Mount Sinai · NIH-11000300 · Data updated 2026-11-12
This study is looking at how the tiny lymphatic vessels in your skin help heal wounds and how they affect the immune system, with the hope of finding better treatments for people with chronic wounds.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $106,164 |
| NIH project number | 5K99AR083536-03 |
| Project ID | NIH-11000300 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic skin wounds or ulcers.
✕Less likely to help
Patients with acute wounds or those not experiencing any skin healing issues may not benefit from this research.
What this research studies
This research investigates the crucial role of lymphatic vessels in the healing process of skin wounds. It aims to explore how these vessels are remodeled during wound healing and how they influence immune cell behavior in damaged tissues. By examining the mechanisms behind lymphatic function and fluid pressure, the research seeks to uncover new insights into chronic wound healing and potential therapeutic targets. Patients with chronic wounds may benefit from the findings, which could lead to improved treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that enhance wound healing and reduce complications for patients with chronic wounds.
How similar studies have gone: While the role of lymphatic vessels in immune function is established, this specific investigation into their remodeling during wound healing is relatively novel and has not been extensively tested.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Konieczny, Piotr — Icahn School of Medicine at Mount Sinai
- Study coordinator: Konieczny, Piotr
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.