Understanding how lymphatic vessels form in the liver
Lymphatics in the liver
['FUNDING_R01'] · YALE UNIVERSITY · NIH-10873261
This study is looking at how new lymphatic vessels form in the liver and how certain cells help with this process, which could lead to new treatments for liver diseases like fibrosis, so patients can hopefully benefit from better care in the future.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | YALE UNIVERSITY (nih funded) |
| Locations | 1 site (NEW HAVEN, UNITED STATES) |
| Trial ID | NIH-10873261 on ClinicalTrials.gov |
What this research studies
This research investigates the formation of new lymphatic vessels in the liver and their role in liver diseases. It focuses on the mechanisms that promote lymphangiogenesis, particularly the involvement of Schwann cells and macrophages in this process. By studying how these cells interact and contribute to lymphatic vessel formation, the research aims to uncover potential therapeutic targets for conditions like liver fibrosis. Patients may benefit from insights that could lead to new treatments for liver-related disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from liver diseases, particularly those with conditions like cirrhosis or liver fibrosis.
Not a fit: Patients with non-liver related conditions or those without significant liver disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve liver health and reduce complications from liver diseases.
How similar studies have performed: Previous research has shown promising results in understanding lymphangiogenesis in other tissues, suggesting potential for success in this novel area of liver research.
Where this research is happening
NEW HAVEN, UNITED STATES
- YALE UNIVERSITY — NEW HAVEN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: IWAKIRI, YASUKO — YALE UNIVERSITY
- Study coordinator: IWAKIRI, YASUKO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.