Understanding how lymphatic networks affect colorectal cancer and its spread
Project-2:Defining the role of compartmentalized neuro-lymphatic networks on CRC and metastatic progression
['FUNDING_OTHER'] · ROCKEFELLER UNIVERSITY · NIH-10909179
This study is looking at how special networks in the intestines help or hurt the spread of colorectal cancer, and it aims to find new ways to prevent and treat this type of cancer by understanding how immune cells work with these networks.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROCKEFELLER UNIVERSITY (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10909179 on ClinicalTrials.gov |
What this research studies
This research investigates the role of specialized lymphatic networks in the intestines and their impact on colorectal cancer (CRC) and its metastatic progression. By examining how immune cells interact with these lymphatic systems, the study aims to uncover mechanisms that could either hinder or promote cancer spread. The approach includes analyzing immune responses and cellular interactions within the gut, which may lead to new insights into CRC prevention and treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those with a family history or other risk factors.
Not a fit: Patients with advanced colorectal cancer who are already undergoing treatment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating colorectal cancer by targeting immune responses.
How similar studies have performed: Other research has shown promising results in understanding immune responses in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- ROCKEFELLER UNIVERSITY — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MUCIDA, DANIEL S — ROCKEFELLER UNIVERSITY
- Study coordinator: MUCIDA, DANIEL S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers