Understanding how lymph nodes influence cancer spread
Project 2 Human Tumor Analysis
This study is looking at how the surroundings of lymph nodes might help cancer spread in people with head and neck or lung cancer, with the hope of finding new ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10931495 on NIH RePORTER |
What this research studies
This research investigates how the environment of lymph nodes can affect the spread of cancer throughout the body. By examining changes in lymph nodes that may promote metastasis, the study aims to identify new biomarkers and potential drug targets. Using advanced imaging techniques and single-cell RNA sequencing, researchers will analyze tumor microenvironments in patients with head and neck squamous cell carcinoma and lung adenocarcinoma. The goal is to uncover the interactions between cancer cells and their surrounding tissues to develop better treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with head and neck squamous cell carcinoma or lung adenocarcinoma.
Not a fit: Patients with cancers not related to the lymph node environment or those without metastatic disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new ways to prevent or treat metastatic cancer, improving survival rates for patients.
How similar studies have performed: Previous research has shown promise in understanding tumor microenvironments and their role in cancer progression, suggesting that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Plevritis, Sylvia Katina — Stanford University
- Study coordinator: Plevritis, Sylvia Katina
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.