Understanding how Lyme disease spreads through ticks and their environment
Investigations of Lyme spirochete transmission as a complex network of microbial and ecological interactions
['FUNDING_R01'] · UNIVERSITY OF RHODE ISLAND · NIH-11132972
This work aims to understand how the bacteria causing Lyme disease are transmitted by blacklegged ticks, looking at the tiny microbes inside the ticks and their interactions with animals in nature.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF RHODE ISLAND (nih funded) |
| Locations | 1 site (KINGSTON, UNITED STATES) |
| Trial ID | NIH-11132972 on ClinicalTrials.gov |
What this research studies
Lyme disease, caused by Borrelia burgdorferi bacteria and spread by blacklegged ticks, is becoming more common. We want to learn more about how these bacteria live inside ticks and how other microbes within the ticks, along with the ticks' interactions with animals, affect the spread of Lyme disease. By studying these complex relationships, we hope to uncover new ways to interrupt the transmission cycle. This involves examining changes in the Lyme bacteria's presence and activity within ticks, considering the influence of other bacteria and the overall tick microbiome.
Who could benefit from this research
Good fit: This foundational research is relevant for anyone concerned about Lyme disease, especially those living in areas where blacklegged ticks are common.
Not a fit: Patients not at risk for Lyme disease or those seeking immediate treatment options may not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of Lyme disease transmission, potentially informing new strategies for prevention and control.
How similar studies have performed: While the specific focus on microbial networks within ticks is novel, previous research has successfully identified key factors in Lyme disease transmission.
Where this research is happening
KINGSTON, UNITED STATES
- UNIVERSITY OF RHODE ISLAND — KINGSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COURET, JANNELLE — UNIVERSITY OF RHODE ISLAND
- Study coordinator: COURET, JANNELLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.