Understanding how Lyme disease bacteria interact with ticks and their environment
Investigations of Lyme spirochete transmission as a complex network of microbial and ecological interactions
['FUNDING_R01'] · UNIVERSITY OF RHODE ISLAND · NIH-10897111
This study is looking at how the bacteria that cause Lyme disease interact with ticks and their tiny living companions to better understand how Lyme disease spreads, which could help find ways to prevent it.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF RHODE ISLAND (nih funded) |
| Locations | 1 site (KINGSTON, UNITED STATES) |
| Trial ID | NIH-10897111 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between the Lyme disease-causing bacteria, Borrelia burgdorferi, and the blacklegged tick, Ixodes scapularis. By examining the tick's microbiome and its ecological relationships, the study aims to understand how these factors influence the transmission of Lyme disease. The researchers will analyze changes in bacterial abundance and gene expression in ticks, focusing on the role of other microbes that may affect the Lyme bacteria's lifecycle. This approach could provide insights into preventing Lyme disease transmission.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in areas where Lyme disease is prevalent, particularly those who have had exposure to ticks.
Not a fit: Patients who do not reside in Lyme disease-endemic areas or who have no history of tick exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing Lyme disease transmission and reducing its incidence.
How similar studies have performed: Previous research has shown success in understanding tick-borne diseases through ecological and microbiome studies, indicating that this approach has potential for meaningful insights.
Where this research is happening
KINGSTON, UNITED STATES
- UNIVERSITY OF RHODE ISLAND — KINGSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COURET, JANNELLE — UNIVERSITY OF RHODE ISLAND
- Study coordinator: COURET, JANNELLE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.