Understanding how lung cells interact with each other
Cell-cell interactions governing lung epithelial progenitor cells
['FUNDING_OTHER'] · BOSTON CHILDREN'S HOSPITAL · NIH-11018523
This study is looking at how certain lung cells work together and respond to their surroundings, which could help us find new ways to treat lung diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11018523 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between lung epithelial progenitor cells and other supporting cell types in the lung using advanced three-dimensional co-culture organoid systems. By modeling how these cells communicate and respond to their environment, the research aims to uncover the molecular signals that regulate lung cell behavior during injury and repair. The study will utilize mouse models and human lung cells to identify mechanisms that could lead to new therapeutic strategies for lung diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with lung diseases or conditions affecting lung function.
Not a fit: Patients with non-lung-related conditions or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for various lung diseases by enhancing our understanding of lung cell interactions.
How similar studies have performed: Previous research has shown promise in using organoid systems to study cell interactions, indicating potential for success in this novel approach.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KIM, CARLA F. — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: KIM, CARLA F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.