Understanding how lung cancer interacts with its environment during treatment
The Delta Ecology of NSCLC Treatment
This study is looking at how non-small cell lung cancer interacts with the surrounding lung environment to understand how tumors grow and change, with the hope of finding better treatment options that are more suited to each patient's unique cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11064240 on NIH RePORTER |
What this research studies
This research investigates the dynamic relationship between non-small cell lung cancer (NSCLC) and the lung microenvironment, focusing on how tumors evolve and respond to treatment. By analyzing changes in both cancer cells and surrounding host cells, the study aims to uncover the ecological factors that influence tumor progression and resistance to therapies. The approach involves using clinical data and various experimental models to quantify and optimize treatment strategies based on these ecological dynamics. Patients may benefit from insights that could lead to more effective treatment options tailored to their specific cancer characteristics.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with non-small cell lung cancer, particularly those with specific driver mutations such as RAS, EGFR, or ALK.
Not a fit: Patients with other types of lung cancer or those who do not have the specific mutations targeted by this research may not benefit from the findings.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with non-small cell lung cancer, potentially enhancing survival rates and quality of life.
How similar studies have performed: Previous research has shown promise in understanding cancer ecology and its impact on treatment outcomes, suggesting that this approach could yield valuable insights.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Anderson, Alexander Robertson Allan — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Anderson, Alexander Robertson Allan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.