Understanding how lung cancer cells interact with their environment during treatment
The Delta Ecology of NSCLC Treatment
['FUNDING_OTHER'] · H. LEE MOFFITT CANCER CTR & RES INST · NIH-10930169
This study is looking at how non-small cell lung cancer cells interact with their surroundings in the lungs to understand what helps or hinders treatment, so we can find better ways to help patients like you respond to therapy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | H. LEE MOFFITT CANCER CTR & RES INST (nih funded) |
| Locations | 1 site (TAMPA, UNITED STATES) |
| Trial ID | NIH-10930169 on ClinicalTrials.gov |
What this research studies
This research investigates the dynamic relationship between non-small cell lung cancer (NSCLC) cells and the lung microenvironment, focusing on how these interactions influence tumor progression and treatment responses. By analyzing changes in the ecology surrounding tumors, the study aims to identify factors that contribute to treatment resistance and success. The approach involves a combination of clinical data analysis, computer modeling, laboratory experiments, and animal studies to develop and validate predictive models for NSCLC treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with non-small cell lung cancer, particularly those with specific driver mutations such as RAS, EGFR, or ALK.
Not a fit: Patients with other types of lung cancer or those who do not have the targeted mutations being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for patients with non-small cell lung cancer by addressing the factors that contribute to treatment resistance.
How similar studies have performed: Previous research has shown promise in understanding tumor microenvironments and their impact on cancer treatment, suggesting that this approach could yield valuable insights.
Where this research is happening
TAMPA, UNITED STATES
- H. LEE MOFFITT CANCER CTR & RES INST — TAMPA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ANDERSON, ALEXANDER ROBERTSON ALLAN — H. LEE MOFFITT CANCER CTR & RES INST
- Study coordinator: ANDERSON, ALEXANDER ROBERTSON ALLAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Treatment