Understanding how low-intensity focused ultrasound affects pain responses in the brain
Mapping the neural and physiologic response to tonic pain with low-intensity focused ultrasound: a bridge towards therapeutic applications
['FUNDING_FELLOWSHIP'] · VIRGINIA POLYTECHNIC INST AND ST UNIV · NIH-11071332
This study is looking at how the brain and body react to pain by using a gentle ultrasound technique to target certain areas in the brain, and it's for people with chronic pain who want to explore new ways to manage their discomfort.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VIRGINIA POLYTECHNIC INST AND ST UNIV (nih funded) |
| Locations | 1 site (BLACKSBURG, UNITED STATES) |
| Trial ID | NIH-11071332 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain and body respond to pain by using low-intensity focused ultrasound (LIFU) to target specific brain regions involved in pain processing. The study aims to map the neural and physiological responses to pain and explore how manipulating these brain areas can change pain experiences. By focusing on the posterior insula and dorsal anterior cingulate cortex, the research seeks to uncover their roles in chronic pain conditions. Participants will undergo non-invasive procedures to help identify potential new treatments for pain management.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who experience chronic pain.
Not a fit: Patients with acute pain or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative non-invasive therapies for managing chronic pain.
How similar studies have performed: Previous research has shown promise in using focused ultrasound for neuromodulation, indicating potential success for this novel approach.
Where this research is happening
BLACKSBURG, UNITED STATES
- VIRGINIA POLYTECHNIC INST AND ST UNIV — BLACKSBURG, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STROHMAN, ANDREW — VIRGINIA POLYTECHNIC INST AND ST UNIV
- Study coordinator: STROHMAN, ANDREW
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: addictive disorder