Understanding how losing social connections affects health
From Social Discruption to Neural Compromise: Establishing Markers and Mediators
This study is looking at how feeling lonely and isolated can affect your body and mind, especially for people with Alzheimer's and similar conditions, to find ways to help improve their health and well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10994162 on NIH RePORTER |
What this research studies
This research investigates the impact of social isolation and loneliness on physical and mental health, particularly in relation to Alzheimer's disease and related dementias. It aims to uncover the biological mechanisms that link the loss of social bonds to inflammation and metabolic changes in the brain. By studying these effects, the research seeks to identify potential pharmacological interventions that could mitigate the health risks associated with loneliness. The goal is to enhance the quality of life for individuals who experience social isolation.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing social isolation or loneliness, particularly those at risk for Alzheimer's disease and related dementias.
Not a fit: Patients who are not experiencing social isolation or who do not have any risk factors for Alzheimer's disease or related dementias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve health outcomes for individuals suffering from loneliness and related health issues.
How similar studies have performed: Previous research has shown promising results in understanding the health impacts of social relationships, suggesting that this approach could yield significant insights.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Glasper, Erica R — Ohio State University
- Study coordinator: Glasper, Erica R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.