Understanding how long to use bisphosphonates for osteoporosis treatment
Calculator for Length of Use of Bisphosphonates (CLUB)
This study is looking at how long older adults should take bisphosphonates to help prevent bone fractures, and whether taking breaks from the medication might be better, so that doctors and patients can make informed choices together.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project ID | NIH-10908436 on NIH RePORTER |
What this research studies
This research investigates the optimal duration of bisphosphonate therapy for preventing osteoporotic fractures, particularly in older adults. It aims to clarify the risks and benefits of long-term use versus taking breaks from the medication, known as drug holidays. The study will involve a diverse group of participants to ensure that findings are applicable across different demographics, including various races, sexes, and those with other health conditions. By analyzing data and outcomes, the research seeks to provide clearer guidelines for patients and healthcare providers regarding bisphosphonate use.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those aged 65 and over, who are at risk for osteoporosis and may be considering bisphosphonate therapy.
Not a fit: Patients who are not at risk for osteoporosis or those who are not eligible for bisphosphonate therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for osteoporosis, reducing the risk of fractures in older adults.
How similar studies have performed: Previous research has shown that understanding the risks and benefits of osteoporosis treatments can lead to better patient outcomes, indicating that this approach has potential for success.
Where this research is happening
Augusta, United States
- Augusta University — Augusta, United States (Active)
Researchers
- Principal investigator: Carbone, Laura D — Augusta University
- Study coordinator: Carbone, Laura D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.