Understanding how long-range inhibitory neurons affect brain function and behavior

Long-range inhibitory neuron circuit organization and cortical function

NIH-funded research Albert Einstein College of Medicine · NIH-11030239

This study is looking at how certain brain cells help control our sleep and wakefulness, and it’s for anyone interested in understanding how our brain works and what might go wrong in conditions that affect our thinking and behavior.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAlbert Einstein College of Medicine NIH-funded
Lab location1 site (Bronx, United States)
Project IDNIH-11030239 on NIH RePORTER

What this research studies

This research investigates the role of long-range inhibitory neurons in the brain and how they influence different behavioral states, such as sleep and wakefulness. By examining the patterns of cortical activity associated with these states, the study aims to uncover how these neurons regulate communication between various brain regions. The methodology includes measuring oscillatory brain activity using techniques like EEG and local field potentials (LFP) to understand the circuits involved in these processes. This research could provide insights into the underlying mechanisms of cognitive functions and disorders related to brain activity.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with autism spectrum disorder (ASD) or related cognitive conditions that may benefit from improved understanding of brain function.

Not a fit: Patients with conditions unrelated to cognitive processing or brain function may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for treating cognitive disorders by targeting the specific neuronal circuits involved.

How similar studies have performed: Previous research has shown promising results in understanding the role of neuronal circuits in cognitive functions, suggesting that this approach could yield valuable insights.

Where this research is happening

Bronx, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions autism spectral disorderautism spectrum disorderAutistic Disorderautistic spectrum disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.