NIH-funded research R01 grant

Understanding how life stress, substance use, and the justice system connect from teen years to adulthood

Official title: Life stress exposures, substance use, and justice system involvement from adolescence to adulthood: Identifying protective factors in a US national cohort study

Funded at Public Health Institute · NIH-11086722 · Data updated 2026-11-12

This project looks at how stressful life events, drug and alcohol use, and involvement with the justice system are connected for young people and adults, hoping to find ways to help.

More Substance Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPublic Health Institute
NIH-funded
Lab location1 site (Oakland, United States)
Project startJuly 1, 2023
Project endMay 31, 2027
Funding year2025
Award (this year)$400,500
NIH project number5R01DA059036-03
Project IDNIH-11086722 on NIH RePORTER

Who could benefit from this research

Could help

This project uses existing data from a national study that followed individuals from adolescence into adulthood, focusing on those who experienced life stress, substance use, and justice system involvement.

Less likely to help

Patients not experiencing life stress, substance use issues, or involvement with the justice system may not directly benefit from the specific findings of this particular analysis.

What this research studies

This project explores why some young adults, particularly those aged 18-25, face higher rates of incarceration, often linked to substance use. We know that many people involved with the justice system have experienced significant life stress. This work aims to understand how different types of stress, from childhood through adulthood, might lead to substance use and, in turn, involvement with the justice system. By looking at existing information from a large national health study, we hope to identify key moments where support and interventions could make a real difference.

Why it matters

Potential benefit: If successful, this work could help identify critical opportunities to intervene and support young people and adults to reduce substance use and justice system involvement.

How similar studies have gone: This project builds upon previous research that has shown connections between adverse childhood experiences and negative health outcomes, but it uniquely examines adult stress exposures and their relevance to incarceration through substance use.

Where this research is happening

  • Public Health Institute
    Oakland, United States
    Active

Researchers

  • Principal investigator: Tam, Christina — Public Health Institute
  • Study coordinator: Tam, Christina

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.