Understanding how knowledge helps struggling middle school readers make inferences

The Role of Knowledge Retrieval in Inference-making among Rural, Middle Grade Struggling Readers

NIH-funded research William Jewell College · NIH-10435063

This study is looking at how well struggling middle school readers can remember what they know and how that helps them make sense of what they read, with the aim of finding ways to help them improve their reading skills.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionWilliam Jewell College NIH-funded
Lab location1 site (Liberty, United States)
Project IDNIH-10435063 on NIH RePORTER

What this research studies

This research investigates how the ability to retrieve knowledge affects the inference-making skills of struggling readers in rural middle schools. It involves two experimental studies: one examining the relationship between knowledge retrieval and inferencing, and another testing an intervention designed to enhance these skills. The study will involve 316 students in grades 5-8, focusing on their reading comprehension and the speed and accuracy of their knowledge retrieval. The goal is to identify effective strategies to support these students in improving their reading abilities.

Who could benefit from this research

Good fit: Ideal candidates for this research are rural middle school students in grades 5-8 who are identified as struggling readers.

Not a fit: Students who are proficient readers or those outside the middle school age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved reading comprehension and academic performance for struggling middle school readers.

How similar studies have performed: Previous research has shown that interventions targeting reading comprehension and inferencing can be effective, suggesting potential for success in this approach.

Where this research is happening

Liberty, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Centers for Disease Control and Prevention (U.S.)Centers for Disease ControlCenters for Disease Control and PreventionUnited States Centers for Disease ControlUnited States Centers for Disease Control and Prevention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.