Understanding how kinesin motors help transport materials within cells
Kinesin Motors and Microtubule-based Trafficking
This study is looking at how tiny proteins help move important materials around inside our cells, which could help us understand diseases like Alzheimer's and cancer better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11062470 on NIH RePORTER |
What this research studies
This research investigates the role of kinesin motor proteins and microtubules in the transport of materials within mammalian cells. By examining how these proteins function and interact with microtubules, the study aims to uncover the mechanisms that drive intracellular trafficking. The researchers will use a combination of biophysical and biochemical techniques alongside cellular assays to explore how defects in these systems can lead to various diseases. This work is particularly relevant for understanding conditions like neurodegenerative diseases and cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by neurodegenerative diseases, developmental disorders, or certain types of cancer.
Not a fit: Patients with conditions unrelated to microtubule dysfunction or kinesin motor activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into the treatment of neurodegenerative diseases and cancers by targeting the cellular transport mechanisms.
How similar studies have performed: Previous research has shown promising results in understanding cellular transport mechanisms, indicating that this approach has potential for success.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Verhey, Kristen J. — University of Michigan at Ann Arbor
- Study coordinator: Verhey, Kristen J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.