Understanding how kidney nerves affect high blood pressure
Renal Sensory Nerve Contribution to Hypertension
This study is looking at how certain nerves in the kidneys can affect blood pressure, and it's designed for anyone interested in understanding how these nerves might help control blood pressure levels.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10898588 on NIH RePORTER |
What this research studies
This research investigates the role of renal sensory nerves in regulating blood pressure, particularly how they may either increase or decrease sympathetic nerve activity. By using rodent models, the study aims to explore the mechanisms by which different receptors on these nerves influence blood pressure levels. The research employs advanced techniques such as radiotelemetry to monitor blood pressure and nerve activity in conscious animals, alongside laboratory methods like imaging and electrophysiology to gain deeper insights into these processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from hypertension or related cardiovascular conditions.
Not a fit: Patients with normal blood pressure or those not affected by cardiovascular diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for hypertension, potentially improving outcomes for patients with high blood pressure.
How similar studies have performed: Previous research has shown promise in understanding the role of renal nerves in blood pressure regulation, suggesting that this approach could yield valuable insights.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Becker, Bryan K — University of Alabama at Birmingham
- Study coordinator: Becker, Bryan K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.