Understanding how kidney blood vessels respond to acute kidney injury
Regulation of Lymphatic and Vascular Remodeling in Acute Kidney Injury
This study is looking at how kidney blood vessels react to sudden kidney injury and how growing lymphatic vessels might help heal the damage, with the hope of finding new treatments that could benefit patients with this condition.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-10876933 on NIH RePORTER |
What this research studies
This research investigates the response of kidney blood vessels to acute kidney injury (AKI), a serious condition affecting many hospitalized patients. The study focuses on the role of lymphatic vessels in the kidneys and how their growth can help mitigate damage caused by AKI. By examining the mechanisms behind blood vessel changes during injury, the research aims to identify new therapeutic strategies to improve kidney health. Patients may benefit from insights that could lead to targeted treatments for AKI.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced acute kidney injury, particularly those hospitalized or critically ill.
Not a fit: Patients with chronic kidney disease who are not currently experiencing acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve kidney function and outcomes for patients suffering from acute kidney injury.
How similar studies have performed: Previous research has shown promise in understanding vascular responses in kidney injury, but this specific approach to studying lymphatic and blood vessel interactions in AKI is relatively novel.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Ghajar-Rahimi, Gelare — University of Alabama at Birmingham
- Study coordinator: Ghajar-Rahimi, Gelare
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.