Understanding how joints develop in the body

Cellular and molecular mechanisms regulating synovial joint development

['FUNDING_CAREER'] · ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED · NIH-10916567

This study is looking at how our joints form in the early stages of development, focusing on the important parts that help them move smoothly, and it aims to help us understand more about joint health for everyone.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED (nih funded)
Locations1 site (STRATFORD, UNITED STATES)
Trial IDNIH-10916567 on ClinicalTrials.gov

What this research studies

This research investigates the cellular and molecular mechanisms involved in the development of synovial joints, which are crucial for movement and overall quality of life. The study focuses on the early stages of joint formation during embryogenesis, particularly how the synovial cavity and its lubricating fluid are created. By examining the role of specific cells and molecules, such as hyaluronan, the research aims to uncover the processes that lead to the formation of functional joints. This could provide insights into joint health and development.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in the biological mechanisms of joint development, particularly those with conditions affecting joint health.

Not a fit: Patients with fully developed joints or those not experiencing joint-related issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding of joint development, potentially informing treatments for joint-related conditions.

How similar studies have performed: While the specific focus on joint development mechanisms is relatively novel, related research has shown success in understanding joint biology and its implications for health.

Where this research is happening

STRATFORD, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.